What is DDAVP used for
DDAVP melt is a sublingual pill also known as desmopressin. It belongs to a class of drugs called synthetic vasopressin analog. It is used to treat patients with central cranial diabetes insipidus, characterized by excessive thirst, increased urination, and bed-wetting. This condition can be caused by brain trauma/brain surgery, genetics, or an infection that has damaged your hypothalamus or pituitary gland.
In addition, this drug helps prevent bleeding due to platelet dysfunction or a deficiency of some blood clotting factors in conditions such as Hemophilia A and von Willebrandâ€™s disease.
How does DDAVP melt work?
Vasopressin is a natural substance in the body that is responsible for controlling the amount of urine. When brain injury or trauma is present, it will affect the hypothalamus or pituitary gland. It will then cause low vasopressin levels leading to increased urination and extreme thirst despite drinking lots of fluids.
Desmopressin functions as an anti-diuretic and an anti-hemorrhagic medication when absorbed into the bloodstream. This drug contains vasopressin that mimics the actions of endogenous anti-diuretic hormone (ADH). The mechanism of action of this drug helps decrease water excretion by increasing water reabsorption in the collecting ducts. As more water returns to the bloodstream, urine concentration rises, water loss is reduced, and extreme thirst is controlled, thereby preventing dehydration.
In addition, this drug has a potent effect in increasing clotting factors (factor VIII) activity in patients with hemophilia and von Willebrand’s disease Type I, thereby reducing the risk of hemorrhage and can also stop active bleeding problems.
The dosage and frequency of desmopressin medication differ from person to person. It will depend on the severity of the patientâ€™s condition, age, and tolerance to the therapy. This medication is available in disintegrating tablets with two strengths: 60 mcg and 120 mcg.
The recommended daily dose for patients with diabetes insipidus is 0.05 mg two times a day. This dosage can be titrated with a maximum intake ranging from 0.1 to 1.2 mg divided into two or three doses.
For patients six years old and above with primary nocturnal emesis (bed wetting), the suggested daily dose is 0.2 mg. This dose can be increased to 0.6 mg per day if an additional response is needed.
Directions on how to use DDAVP Melt
Read all Ddavp Melt medication guidelines and use it precisely as instructed. If you have any queries or are unsure how to administer this medicine, consult your physician or pharmacist.
Take Ddavp Melt by mouth by placing it under the tongue two or three times a day for diabetes insipidus, while for bed wetting therapy, take this drug once a day at bedtime or as directed by your primary care provider. Note that this drug does not need water because it quickly melts on its own.
When taking Ddavp Melt, make sure to limit your water or fluid intake, depending on your doctor. Administer this drug regularly to prevent missing a dose. Setting a reminder on your phone will make it easier for you not to miss a pill. If you fail to take Ddavp melt, take it as soon as possible, but if it is nearing your next dose, skip it and resume your regular schedule.
DDAVP Melt side effects
The following are the common desmopressin side effects that may resolve with time without medical intervention:
- Stomach upset
- Dry mouth
- Nasal congestion
If any of these side effects worsen or if you experience the following serious drug reactions, contact your doctor immediately:
- Low levels of sodium symptoms: headache, confusion, hallucinations, muscle cramps, severe weakness, vomiting, loss of coordination, or restlessness
- Rapid weight gain
- Severe headache
- Breathing problems
- Mood changes
- Visual disturbances
- Swelling (lower and upper extremities)
- High blood pressure
Bear in mind that this is not all the list of the potential health concerns linked with Ddavp Melt.
DDAVP Melt Warnings
Before beginning this therapy, tell your doctor if you have an electrolyte imbalance, fluid retention, congestive heart failure, high blood pressure, cystic fibrosis, urination problems, or kidney disease. Informing your physician will enable them to determine if this drug is safe for your illness.
Do not use Ddavp Melt if you have severe kidney problems or low sodium levels (hyponatremia) to prevent aggravating your health condition.
Do not take this drug if you are allergic to desmopressin or other Ddavp ingredients, do not use this drug. When taking this drug, seek emergency medical attention as soon as you notice the following allergic reactions: rashes, hives, swelling of the face and lips, throat tightness, or trouble breathing.
Use caution when using Ddavp Melt on young individuals, as they are more sensitive to the side effects of this medication.
Use caution when using this drug with older adults as renal function deteriorates as you age. Because the kidneys are responsible for theÂ excretion of this drug, they are more susceptible to electrolyte imbalance and low serum sodium levels.
Before administering this therapy, conditions like dehydration are treated or addressed first.
Do not use this drug together with loop diuretics, systemic, or inhaled glucocorticoids. Doing so will increase your risk of severe hyponatremia.
Monitor serum sodium and blood pressure levels more frequently in patients taking desmopressin to prevent life-threatening effects of a drug interaction.
Keep and store this drug accordingly, away from the reach of the children.
DDAVP Price in Canada
The Canadian government controls the pricing of medicines in the country, including Ddavp Melt, making this medicine much more affordable than in other countries.
The price of this cream varies depending on the strength and quantity you are going to buy. We offer quality products at a very reasonable value.
Frequently asked questions
When is the best time to give Ddavp Melt to young individuals?
When taking Ddavp Melt, make sure to limit their liquids after supper, one hour before bedtime, until the following morning (at least eight hours). Doing so will decrease the risk of water intoxication and hyponatremia that may lead to convulsions.
Where to buy Ddavp Melt?
Generally, there are a handful of online and local pharmacies dispensing this medication. OnlineCanadianPharmacy.com offers a safe, fast and hassle-free transaction so you can get your treatment started right away.
How quickly does Ddavp melt work?
The effects of Ddavp differ from person to person, depending on how your body responds to the medication. Usually, this medication peaks after 30 minutes of using it.
What should I do if I have taken too much Ddavp Melt?
For drug overdose, immediately call your doctor or Poison Control Center for help. Closely watch out for drug overdose symptoms, such as headache, nausea, vomiting, abdominal cramps, facial flushing, weight gain due to water retention, and convulsions.