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Indications

• Promacta is indicated for the treatment of thrombocytopenia in patients with chronic immune thrombocytopenia (ITP) who have had an inadequate response to other treatments.
• It is prescribed to help increase platelet counts in patients with ITP, reducing the risk of bleeding episodes and the need for platelet transfusions.
• Promacta may also be used to treat thrombocytopenia in patients with chronic hepatitis C virus (HCV) infection to allow the initiation and maintenance of interferon-based therapy.

Dosage and administration

• The recommended dosage of Promacta for the treatment of chronic immune thrombocytopenia (ITP) is individualized based on the patient’s platelet count and response to treatment.
• Typically, the initial dosage of Promacta is 50 milligrams (mg) orally once daily.
• The dosage may be adjusted by the healthcare provider based on the patient’s platelet count, with a maximum recommended dosage of 75 mg once daily.
• Promacta should be taken on an empty stomach at least 1 hour before or 2 hours after eating food or consuming dairy products or calcium-fortified beverages.
• Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.
• It is important to take Promacta regularly to achieve and maintain optimal platelet counts.
• If a dose of Promacta is missed, take it as soon as remembered, unless it is almost time for the next scheduled dose. Do not double the dose to catch up.
• If you have any questions or concerns about the dosage or administration of Promacta, consult your healthcare provider.

Side effects

• Common side effects of Promacta may include headache, fatigue, nausea, and diarrhea.
• Some individuals may experience changes in liver function tests or elevated liver enzymes while taking Promacta.
• Promacta may increase the risk of blood clots, particularly in patients with certain risk factors or at higher dosages.
• Other potential side effects include muscle aches, dizziness, and upper respiratory tract infections.
• In rare cases, Promacta may lead to more serious side effects such as allergic reactions, including rash, itching, or swelling of the face, lips, or tongue.
• Patients should promptly report any unusual or severe side effects to their healthcare provider.

Precautions

• Inform your healthcare provider about any history of liver disease, blood clots, or bleeding disorders before starting Promacta.
• Use caution when taking Promacta if you have a history of cardiovascular disease or risk factors for blood clots, such as smoking or obesity.
• Discuss with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding before using Promacta, as it may affect fetal development or breast milk production.
• Be aware that Promacta may interact with other medications, so inform your healthcare provider about all medications you are currently taking, including prescription, over-the-counter, and herbal supplements.
• Regular monitoring of liver function tests, platelet counts, and signs of bleeding or clotting may be necessary while taking Promacta.
• If you experience symptoms such as unusual bruising or bleeding, severe headache, chest pain, or shortness of breath while taking Promacta, seek immediate medical attention.
• Keep Promacta out of reach of children and pets and store it at room temperature away from moisture and heat sources.