Lubiprostone is used for treating chronic idiopathic constipation and irritable bowel syndrome with constipation.
It is also used to address constipation caused by opioid medications in individuals with ongoing pain due to non-cancer medical conditions.
The medication improves symptoms such as bloating, abdominal discomfort, and difficulty passing stool.
It enhances stool texture and reduces the need to strain during bowel movements.
Lubiprostone belongs to the chloride channel activators drug class.
It works by increasing fluid within the intestines, making the passage of stool easier.
Dosage and administration
Take the medication by mouth with food and water, twice daily.
Swallow the medication whole; do not break or chew it.
Dosage is determined by your medical condition and response to treatment.
Use the medication regularly at the same times each day for maximum benefit.
Discuss the need for continued treatment with your doctor regularly.
Inform your doctor if your condition persists or worsens.
Side effects
Common side effects may include nausea, diarrhea, gas, vomiting, dry mouth, runny nose, cough, fever, headache, joint/back pain, or trouble sleeping.
Inform your doctor if these side effects persist or worsen.
This medication is prescribed because its benefits outweigh potential risks for most people.
Serious side effects include swelling of arms/legs and mental/mood changes; contact your doctor if experienced.
Lubiprostone may cause low blood pressure and fainting; stop taking it and notify your doctor if severe diarrhea/vomiting occurs.
Rarely, trouble breathing, and chest tightness may occur, usually within 30 to 60 minutes after the first dose; seek medical help for persistent symptoms.
A severe allergic reaction is rare but requires immediate medical attention; symptoms include rash, itching/swelling, severe dizziness, and trouble breathing.
Precautions
Inform your doctor or pharmacist about any allergies to lubiprostone or other substances.
Discuss your medical history, especially stomach/intestinal issues and liver disease, before using this medication.
Before surgery, disclose all products you use, including prescriptions, over-the-counter drugs, and herbal products.
Use this medication during pregnancy only if necessary; consult your doctor about the potential risks and benefits.
It is unclear if the drug passes into breast milk, but it may have undesired effects on a nursing infant; consult your doctor before breastfeeding.
Additional information
Brand Name:
Amitiza
Scientific Name:
Lubiprostone
Other Names:
Amitiza, Lubowel
Strength(s):
8mcg, 24mcg
Quantities Available:
60, 180
Formulation:
Capsule, Soft Gelatin Capsule
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Amitiza
Lubiprostone
