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Rapamune is used to lower your body’s immune system to prevent your body from rejecting an organ transplant.

Keep Rapamune tablets at room temperature and protect from heat, moisture, and light.

Let your doctor know if you are allergic to any drugs or you have high cholesterol or triglycerides; cytomegalovirus; liver disease; or kidney disease. Rapamune may increase the chances of developing lymphoma or other forms of cancer. Tell your doctor if you are pregnant, planning on becoming pregnant, or are breast-feeding. Rapamune may be harmful to an unborn baby. Use an effective form of birth control while taking Rapamune.

Do not mix this medication with grapefruit juice as potentially dangerous side effects may occur. Avoid eating or drinking grapefruit juice. Rapamune can lower the blood cells that fight infections. Avoid contact with people who have colds, the flu, or other contagious illnesses. Do not receive any vaccinations unless told so by your doctor. If you notice any signs of an infection, contact your doctor immediately. Try to avoid exposure to sunlight or artificial UV rays, such as those in tanning beds. When you go outside, always remember to wear sunscreen and protective clothing.

Patient Family Information  : Always take Rapamune exactly as your doctor has shown you. Take Rapamune with a glass of water. Do not crush, chew, or break a Rapamune tablet. You may take Rapamune with or without food.

Avoid the use of Rapamune if you are allergic to sirolimus.

Sever Side Effects : Serious side effects may include: allergic reaction; fast heart rate; pain when you breathe, feeling short of breath; chest pain, feeling weak or tired; coughing up mucus or blood; feeling like you might pass out; pale skin, easy bruising or bleeding, wea

Less severe side effects may include: joint pain; nausea, vomiting, diarrhea, constipation, stomach pain; headache; or acne or skin rash.

Other: None.

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