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• Read the Medication Guide provided by your pharmacist before starting omeprazole and with each refill; consult your doctor or pharmacist if you have questions.
• Take this medication orally before a meal as directed by your doctor, usually once daily. Dosage and treatment duration depend on your medical condition and response. In children, dosage is weight dependent.
• If taking orally, empty the packet into a container with 1 to 3 teaspoons (5 to 15 milliliters) of water, following package directions. Stir well, let it thicken for 2 to 3 minutes, stir again, and consume the mixture within 30 minutes. If any medication remains, add more water, stir, and drink immediately. Do not crush or chew the granules.
• If administering through a tube, consult your healthcare professional for proper mixing and administration instructions.
• If necessary, antacids may be taken alongside omeprazole. If also taking sucralfate, take omeprazole at least 30 minutes before sucralfate.
• Use regularly at the same time each day for maximum benefit. Continue treatment for the prescribed duration, even if symptoms improve.
• Inform your doctor if your condition persists or worsens. The risk of side effects increases over time. Ask your doctor about the recommended duration of treatment.

• Possible side effects of omeprazole include headache or abdominal pain; inform your doctor or pharmacist if these persist or worsen.
• This medication is prescribed because the benefits are considered greater than the risk of side effects; many users do not experience serious side effects.
• Notify your doctor immediately if you have serious side effects such as symptoms of low magnesium levels or signs of lupus.
• Omeprazole may rarely cause a severe intestinal condition due to C. difficile bacteria; contact your doctor if you develop persistent diarrhea, abdominal pain/cramping, or blood/mucus in your stool.
• Avoid using anti-diarrhea or opioid products if you experience these symptoms, as they may worsen the condition.
• Proton pump inhibitors like omeprazole may rarely lead to vitamin B-12 deficiency, especially with long-term daily use (3 years or longer); inform your doctor if you develop symptoms of B-12 deficiency.
• A very serious allergic reaction is rare but seek medical help if you notice symptoms like fever, swollen lymph nodes, rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, or signs of kidney problems.
• This list may not include all possible side effects; contact your doctor or pharmacist for any unlisted effects.

• Before taking omeprazole, inform your doctor or pharmacist of any allergies to it or similar drugs (e.g., esomeprazole, lansoprazole, pantoprazole) and other allergies. Inactive ingredients may cause allergic reactions; consult your pharmacist for more information.
• Disclose your medical history, especially liver disease or lupus, before using this medication.
• Seek immediate medical help if you experience heartburn with lightheadedness/sweating/dizziness, or chest/jaw/arm/shoulder pain, especially with shortness of breath, unusual sweating, or unexplained weight loss.
• Inform your doctor or dentist about all products you use, including prescription drugs, nonprescription drugs, and herbal products, before having surgery.
• Proton pump inhibitors like omeprazole may increase the risk of bone fractures, especially with prolonged use, higher doses, and in older adults. Discuss preventive measures such as calcium and vitamin D supplements with your doctor or pharmacist.
• Older adults may be more sensitive to side effects, including bone loss, fractures, and C. difficile infection.
• Children may be more sensitive to side effects, especially fever, cough, and infections of the nose/throat/airways.
• Use this medication during pregnancy only when necessary; discuss risks and benefits with your doctor.
• Omeprazole passes into breast milk, and the effects on a nursing infant are unknown. Consult your doctor before breastfeeding.

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