Alendronate is used for the prevention and treatment of certain types of bone loss (osteoporosis) in adults.
Osteoporosis leads to thinner bones that are more prone to fractures.
Risk of osteoporosis increases with age, post-menopause, or prolonged use of corticosteroid medications like prednisone.
The medication slows down bone loss, aiding in the maintenance of strong bones and decreasing the risk of fractures.
Alendronate falls under the category of drugs known as bisphosphonates.
Dosage and administration
Read the Medication Guide provided by the pharmacist before starting alendronate and with each refill.
Follow instructions closely to ensure maximum drug absorption and reduce the risk of esophageal injury.
If questions arise, consult your doctor or pharmacist.
Take the medication orally once a day, in the morning before consuming food, beverages, or other medications.
Use a full glass (6-8 ounces or 180-240 milliliters) of plain water to swallow the tablet whole; do not chew or suck on it.
Stay fully upright (sitting, standing, or walking) for at least 30 minutes after taking, and do not lie down until after the first meal of the day.
Alendronate is effective only on an empty stomach, so wait at least 30 minutes (preferably 1 to 2 hours) before eating or drinking anything other than plain water.
Avoid taking the medication at bedtime or before getting up for the day to ensure absorption and prevent side effects.
Calcium or iron supplements, vitamins, antacids, coffee, tea, soda, mineral water, calcium-enriched juices, and food can decrease alendronate absorption; wait at least 30 minutes (preferably 1 to 2 hours) after taking alendronate before consuming these.
Take the medication regularly at the same time each morning for optimal benefits.
Discuss with your doctor the risks and benefits of long-term use of alendronate.
Side effects
Possible common side effects: stomach pain, constipation, diarrhea, gas, or nausea
Inform your doctor or pharmacist promptly if these effects persist or worsen.
Medication prescribed based on the doctor’s judgment that benefits outweigh risks; many users do not experience serious side effects.
Immediate reporting to the doctor for serious side effects: jaw/ear pain, increased or severe bone/joint/muscle pain, new or unusual hip/thigh/groin pain, swelling of joints/hands/ankles/feet, black/tarry stools, vomit resembling coffee grounds.
Rare but serious esophageal irritation and ulcers may occur; stop taking alendronate and contact your doctor or pharmacist immediately if experiencing new or worsening heartburn, chest pain, or pain/difficulty swallowing.
Very rare but serious allergic reactions may occur; seek medical help immediately for symptoms such as rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.
Incomplete list of possible side effects; contact your doctor or pharmacist for any unlisted effects.
Precautions
Inform your doctor or pharmacist about any allergies to alendronate, other bisphosphonates, or other substances.
Discuss your medical history, especially esophageal disorders, trouble swallowing, difficulty standing or sitting upright for at least 30 minutes, low calcium levels, kidney problems, and stomach/intestinal disorders.
Serious jawbone problems may occur in some individuals taking alendronate; your doctor should check your mouth before starting the medication. Inform your dentist about the medication before dental work, have regular dental exams, and maintain oral health to prevent jawbone issues. Report jaw pain to your doctor and dentist promptly.
Before any surgery, especially dental procedures, inform your doctor and dentist about alendronate and all other products used, and follow instructions regarding medication cessation before surgery.
Not recommended for use in children due to severe side effects observed in studies, such as vomiting, fever, and flu-like symptoms.
Inform your doctor if you are pregnant or planning to become pregnant. Alendronate may remain in the body for an extended period, and pregnancy is not recommended while using it. Discuss risks and benefits with your doctor.
Unknown if alendronate passes into breast milk; consult your doctor before breastfeeding.
Additional information
Brand Name:
Fosamax
Scientific Name:
Alendronate
Other Names:
Alendronate, Alendronic Acid, Fosamax, Osteofos
Strength(s):
10mg, 35mg, 70mg
Quantities Available:
4, 12, 100
Formulation:
Tablet
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Fosamax
Alendronate
