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Indications

• Powder form of diclofenac used to treat migraine headaches.
• Diclofenac is not for preventing or reducing the frequency of migraines.
• Classified as a nonsteroidal anti-inflammatory drug (NSAID).
• Mechanism: Blocks the body’s production of natural substances causing inflammation.
• Result: Reduction in swelling, pain, and fever.

Dosage and administration

• Read the Medication Guide from the pharmacist before starting diclofenac and with each refill.
• Take the medication orally as directed by the doctor.
• Do not exceed one packet per migraine attack, as per the manufacturer’s recommendation.
• Empty one packet into 1-2 ounces of water, mix, and drink immediately; do not mix with liquids other than water.
• If stomach upset occurs, take with food, milk, or an antacid. Avoid taking with a high-fat meal, as it may reduce effectiveness.
• Different brands/forms of diclofenac have varying effects; do not switch forms without doctor’s approval.
• Take the lowest effective dose to reduce the risk of side effects; do not increase dose or frequency without prescription.
• Use pain medication at the first signs of pain or migraine for optimal effectiveness.
• Using migraine drugs on 10 or more days monthly may worsen headaches (medication overuse headache); do not exceed prescribed usage and inform the doctor if needed or if the medication is not effective.

Side effects

• Possible side effects: upset stomach, nausea, vomiting, heartburn, diarrhea, constipation, gas, headache, drowsiness, dizziness, blurred vision.
• Inform the doctor/pharmacist if these effects persist or worsen.
• Medication prescribed based on the doctor’s judgment of benefits outweighing risks.
• Some may experience high blood pressure; monitor regularly and report elevated results.
• Report serious side effects promptly: hearing changes, mental/mood changes, easy bleeding/bruising, difficult/painful swallowing, symptoms of heart failure.
• Seek immediate medical help for very serious side effects: signs of kidney problems, unexplained stiff neck, symptoms of liver disease.
• Rare but serious allergic reactions may occur; seek immediate medical help for symptoms like fever, swollen lymph nodes, rash, itching/swelling, severe dizziness, trouble breathing.
• Incomplete list; contact doctor/pharmacist for other unlisted effects.

Precautions

• Inform the doctor/pharmacist about allergies to diclofenac, aspirin, or other NSAIDs.
• Inactive ingredients may cause allergic reactions; consult the pharmacist for details.
• Share medical history, especially asthma, blood disorders, nasal polyps, heart disease, high blood pressure, liver disease, stroke, and stomach/intestinal/esophagus problems.
• Kidney problems may occur with NSAID use, higher risk with dehydration, heart failure, kidney disease, age, or certain medications. Drink fluids to prevent dehydration.
• Dizziness, drowsiness, and blurred vision may result; avoid driving or using machinery until safe. Limit alcohol and discuss marijuana use with the doctor.
• Potential for stomach bleeding; daily alcohol/tobacco use may increase risk. Limit alcohol and quit smoking.
• Increased sun sensitivity: limit sun exposure, use sunscreen, and wear protective clothing. Report sunburn or skin issues.
• Contains aspartame; consult the doctor/pharmacist if phenylketonuria or aspartame avoidance is necessary.
• Before surgery, inform the doctor/dentist about all medications, including prescription, non-prescription, and herbal products.
• Older adults may face increased risks of stomach bleeding, kidney problems, heart attack, and stroke.
• Women of childbearing age should discuss benefits and risks with the doctor; inform about pregnancy or plans to become pregnant. Use the lowest effective dose if needed between 20 and 30 weeks of pregnancy; avoid after 30 weeks.
• Medication passes into breast milk; consult the doctor before breastfeeding.