Indications
- Trileptal is indicated for the treatment of partial seizures in adults and children aged 4 years and older.
- It is prescribed as monotherapy or adjunctive therapy in the management of epilepsy, including partial seizures, generalized tonic-clonic seizures, and mixed seizure patterns.
- Trileptal may also be used off-label for the treatment of bipolar disorder and neuropathic pain.
Dosage and administration
- The dosage of Trileptal varies depending on the patient’s age, weight, and medical condition.
- For adults and children aged 12 years and older, the recommended starting dosage is typically 600 mg taken orally twice daily.
- The dosage may be adjusted based on the patient’s response to treatment and tolerance, with a maximum recommended dosage of 2400 mg per day.
- For children aged 4 to 12 years, the recommended starting dosage is typically 8-10 mg/kg/day taken orally twice daily.
- The dosage may be increased gradually based on the patient’s weight and response to treatment, with a maximum recommended dosage of 46 mg/kg/day.
- Trileptal tablets should be swallowed whole with a glass of water and can be taken with or without food.
- The suspension form of Trileptal should be shaken well before each use, and the prescribed dose should be measured using the provided dosing syringe or spoon.
- If a dose of Trileptal is missed, it should be taken as soon as remembered, unless it is almost time for the next dose. In that case, the missed dose should be skipped, and the regular dosing schedule resumed.
- Patients should not double the dose to make up for a missed one.
- If there are any questions or concerns about the dosage or administration of Trileptal, patients should consult their healthcare provider or pharmacist for guidance.
Side effects
- Common side effects of Trileptal may include dizziness, drowsiness, or headache.
- Some individuals may experience fatigue, nausea, or vomiting while taking Trileptal.
- Trileptal can cause gastrointestinal disturbances, such as abdominal pain, diarrhea, or constipation.
- It may also lead to hyponatremia (low sodium levels), which can manifest as confusion, weakness, or seizures.
- Trileptal may increase the risk of allergic reactions, including rash, itching, or swelling of the face, lips, or throat.
- Rarely, Trileptal may cause serious side effects such as Stevens-Johnson syndrome or toxic epidermal necrolysis.
- Contact your healthcare provider if you experience any persistent or severe side effects while taking Trileptal.
Precautions
- Inform your healthcare provider about any existing medical conditions, especially kidney disease, liver disease, or hyponatremia, before taking Trileptal.
- Let your healthcare provider know if you are pregnant, planning to become pregnant, or breastfeeding, as the safety of Trileptal during pregnancy or lactation has not been established.
- Inform your healthcare provider if you have a history of allergies to medications or any other substances, as Trileptal may contain inactive ingredients that can cause allergic reactions.
- Use caution when taking Trileptal if you have a history of depression or suicidal thoughts, as it may increase the risk of mood changes or suicidal behavior.
- Monitor for signs and symptoms of hyponatremia, such as headache, confusion, or seizures, while taking Trileptal.
- Avoid abrupt discontinuation of Trileptal without consulting your healthcare provider, as it may lead to withdrawal symptoms or worsening of seizures.
- Use caution when driving or operating machinery after taking Trileptal, as it may cause dizziness or drowsiness in some individuals.
- Inform your healthcare provider about all medications, supplements, and herbal remedies you are taking, as they may interact with Trileptal and affect its effectiveness or increase the risk of side effects.
- Keep Trileptal out of reach of children and pets and store it at room temperature away from moisture and heat.
- Follow up with your healthcare provider regularly to monitor your response to Trileptal and adjust the treatment plan as needed.