Prometrium is indicated for the treatment of secondary amenorrhea (absence of menstrual periods) in women of reproductive age.
It is prescribed to help induce menstrual periods in women who have not experienced a menstrual cycle for several months but are not pregnant.
Prometrium may also be used as part of hormone replacement therapy (HRT) in menopausal women with an intact uterus to help reduce symptoms such as hot flashes and vaginal dryness.
Dosage and administration
The recommended dosage of Prometrium for the treatment of secondary amenorrhea is 200 milligrams (mg) orally once daily at bedtime for 12 to 14 consecutive days per 28-day cycle.
For hormone replacement therapy (HRT) in menopausal women with an intact uterus, the usual dosage of Prometrium is 200 mg orally once daily at bedtime for 12 to 14 consecutive days per 28-day cycle.
Prometrium may be taken with or without food.
Swallow the capsule whole with a full glass of water. Do not crush, chew, or break the capsule.
Follow the dosage instructions provided by your healthcare provider carefully.
If you have any questions or concerns about the dosage or administration of Prometrium, consult your healthcare provider.
Side effects
Common side effects of Prometrium may include:
Headache
Breast tenderness
Nausea
Bloating
Abdominal pain or cramping
Dizziness
Fatigue
Some individuals may experience changes in menstrual bleeding patterns, such as breakthrough bleeding or spotting, while taking Prometrium.
Other potential side effects include:
Mood changes
Vaginal discharge or irritation
Joint or muscle pain
Changes in appetite or weight
In rare cases, Prometrium may lead to more serious side effects such as allergic reactions, including rash, itching, or swelling of the face, lips, or tongue.
Patients should promptly report any unusual or severe side effects to their healthcare provider.
Precautions
Inform your healthcare provider about any history of blood clots, stroke, heart disease, breast cancer, or liver problems before starting Prometrium.
Use caution when taking Prometrium if you have a history of depression, migraines, or asthma, as it may exacerbate these conditions.
Discuss with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding before using Prometrium, as it may affect fetal development or breast milk production.
Be aware that Prometrium may interact with other medications, so inform your healthcare provider about all medications you are currently taking, including prescription, over-the-counter, and herbal supplements.
Regular monitoring of hormone levels and breast examinations may be necessary while taking Prometrium, especially in menopausal women receiving hormone replacement therapy (HRT).
If you experience symptoms such as sudden severe headache, chest pain, or difficulty breathing while taking Prometrium, seek immediate medical attention.
Keep Prometrium out of reach of children and pets and store it at room temperature away from moisture and heat sources.
Additional information
Brand Name:
Prometrium
Scientific Name:
Progesterone
Other Names:
Endogest, Progestan, Utrogestan
Strength(s):
100mg, 200mg
Quantities Available:
90, 100
Formulation:
Capsule, Soft Gel Caps, Soft Gel Capsules
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Prometrium
Progesterone
